Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling

Medicine & Life Sciences

• Apoptosis 8%
• Apoptosis Regulatory Proteins 68%
• Autophagy 55%
• Autophagy-Related Protein 12 14%
• Autophagy-Related Protein 5 12%
• Beclin-1 18%
• Breast Neoplasms 4%
• Cell Death 5%
• Cell Line 4%
• Cell- and Tissue-Based Therapy 6%
• Everolimus 27%
• Fibroblasts 5%
• Gamma Rays 8%
• Lung Neoplasms 5%
• Neoplasms 18%
• Radiation 5%
• Small Interfering RNA 6%
• Therapeutics 9%
• TOR Serine-Threonine Kinases 64%
• Tumor Cell Line 7%
• Up-Regulation 5%

Chemical Compounds

• Cell Death 30%
• Mammalian Target of Rapamycin Inhibitor 100%
• Protein 23%
• Reaction Yield 11%
• Sensitization 61%
• Small Interfering RNA 39%