Abstract
(equation presented) The title compound, a potent protein phosphatase inhibitor and anticancer agent, was prepared by an efficient, multiconvergent asymmetric synthesis. Key transformations include a ring forming olefin metathesis leading to the α,β-unsaturated lactone and creation of the triene moiety via Suzuki cross-coupling.
Original language | English (US) |
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Pages (from-to) | 969-971 |
Number of pages | 3 |
Journal | Organic Letters |
Volume | 4 |
Issue number | 6 |
DOIs | |
State | Published - Mar 21 2002 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry