Association between telomere length and cognitive ability in a community-based sample

Rishika Kaja; Stephanie M. Reyes; Heidi Rossetti; Edson S Brown

doi:10.1016/j.neurobiolaging.2018.11.006

Association between telomere length and cognitive ability in a community-based sample

Rishika Kaja, Stephanie M. Reyes, Heidi Rossetti, Edson S Brown

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Prior research suggests that telomere length is a biomarker of cognitive aging; however, literature has demonstrated conflicting findings to date. The present study uses data from the Dallas Heart Study, N = 2606, to assess the association between telomere length and cognitive ability on the Montreal Cognitive Assessment. The data do not support a relationship between telomere length and general cognitive functioning, (β = 0.016, SE = 0.31, p = 0.407). The data further replicate the negative findings within current literature.

Original language	English (US)
Pages (from-to)	51-53
Number of pages	3
Journal	Neurobiology of Aging
Volume	75
DOIs	https://doi.org/10.1016/j.neurobiolaging.2018.11.006
State	Published - Mar 2019

Keywords

Cellular biomarker
Cognitive ability
Cognitive aging
Community-based sample
Telomere

ASJC Scopus subject areas

Neuroscience(all)
Aging
Clinical Neurology
Developmental Biology
Geriatrics and Gerontology

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10.1016/j.neurobiolaging.2018.11.006

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title = "Association between telomere length and cognitive ability in a community-based sample",

abstract = "Prior research suggests that telomere length is a biomarker of cognitive aging; however, literature has demonstrated conflicting findings to date. The present study uses data from the Dallas Heart Study, N = 2606, to assess the association between telomere length and cognitive ability on the Montreal Cognitive Assessment. The data do not support a relationship between telomere length and general cognitive functioning, (β = 0.016, SE = 0.31, p = 0.407). The data further replicate the negative findings within current literature.",

keywords = "Cellular biomarker, Cognitive ability, Cognitive aging, Community-based sample, Telomere",

author = "Rishika Kaja and Reyes, {Stephanie M.} and Heidi Rossetti and Brown, {Edson S}",

note = "Funding Information: This work was supported, in part, by the Science Teacher Access to Resources at Southwestern (STARS) program and the National Center for Advancing Translational Sciences of the National Institutes of Health, United States under award number UL1TR001105 . Funding Information: Dr Brown has research grants from NIH, the Stanley Medical Research Institute, and Otsuka and serves on an advisory board for Allergan. Dr Rossetti, Ms. Kaja, and Ms. Reyes have nothing to declare. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Publisher Copyright: {\textcopyright} 2018",

year = "2019",

month = mar,

doi = "10.1016/j.neurobiolaging.2018.11.006",

language = "English (US)",

volume = "75",

pages = "51--53",

journal = "Neurobiology of Aging",

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T1 - Association between telomere length and cognitive ability in a community-based sample

AU - Kaja, Rishika

AU - Reyes, Stephanie M.

AU - Rossetti, Heidi

AU - Brown, Edson S

N1 - Funding Information: This work was supported, in part, by the Science Teacher Access to Resources at Southwestern (STARS) program and the National Center for Advancing Translational Sciences of the National Institutes of Health, United States under award number UL1TR001105 . Funding Information: Dr Brown has research grants from NIH, the Stanley Medical Research Institute, and Otsuka and serves on an advisory board for Allergan. Dr Rossetti, Ms. Kaja, and Ms. Reyes have nothing to declare. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Publisher Copyright: © 2018

PY - 2019/3

Y1 - 2019/3

N2 - Prior research suggests that telomere length is a biomarker of cognitive aging; however, literature has demonstrated conflicting findings to date. The present study uses data from the Dallas Heart Study, N = 2606, to assess the association between telomere length and cognitive ability on the Montreal Cognitive Assessment. The data do not support a relationship between telomere length and general cognitive functioning, (β = 0.016, SE = 0.31, p = 0.407). The data further replicate the negative findings within current literature.

AB - Prior research suggests that telomere length is a biomarker of cognitive aging; however, literature has demonstrated conflicting findings to date. The present study uses data from the Dallas Heart Study, N = 2606, to assess the association between telomere length and cognitive ability on the Montreal Cognitive Assessment. The data do not support a relationship between telomere length and general cognitive functioning, (β = 0.016, SE = 0.31, p = 0.407). The data further replicate the negative findings within current literature.

KW - Cellular biomarker

KW - Cognitive ability

KW - Cognitive aging

KW - Community-based sample

KW - Telomere

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DO - 10.1016/j.neurobiolaging.2018.11.006

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AN - SCOPUS:85057991460

SN - 0197-4580

VL - 75

SP - 51

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JO - Neurobiology of Aging

JF - Neurobiology of Aging

ER -

Association between telomere length and cognitive ability in a community-based sample

Abstract

Keywords

ASJC Scopus subject areas

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