TY - GEN
T1 - Arteries engineered from vascular cells
AU - Niklason, L. E.
AU - Gao, Jinming
AU - Abbott, William
AU - Hirschi, Karen
AU - Houser, Stuart
AU - Marini, Robert
AU - Langer, Robert
N1 - Copyright:
Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.
PY - 1999
Y1 - 1999
N2 - A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.
AB - A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.
UR - http://www.scopus.com/inward/record.url?scp=0033353988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033353988&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0033353988
SN - 0780356756
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 747
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PB - IEEE
T2 - Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
Y2 - 13 October 1999 through 16 October 1999
ER -