Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest

Medicine & Life Sciences

• Aromatic Hydrocarbons 100%
• Retinoblastoma Protein 86%
• Cell Cycle Checkpoints 66%
• Polychlorinated Dibenzodioxins 20%
• Cell Cycle 12%
• Cytoplasmic and Nuclear Receptors 10%
• 1,4-dioxin 8%
• Proteins 7%
• Dioxins 6%
• Breast Neoplasms 6%
• Two-Hybrid System Techniques 6%
• Peptide Receptors 6%
• Viral Tumor Antigens 6%
• Ectopic Gene Expression 5%
• Thymocytes 5%
• MCF-7 Cells 5%
• Osteosarcoma 5%
• Keratinocytes 5%
• In Vitro Techniques 4%
• Cultured Cells 4%
• Estrogens 4%
• Poisons 3%
• Apoptosis 3%
• Animals 2%

Chemical Compounds

• Arene 54%
• Protein 28%
• Teratogenic 8%
• Heterodimerization 7%
• Apoptosis Induction 7%
• Carcinogenic 5%
• Toxic 3%
• Chemical Transformation 3%