Approaches to reducing radiation dose from radionuclide nyocardial perfusion imaging

Sharmila Dorbala, Ron Blankstein, Hicham Skali, Mi Ae Park, Jolene Fantony, Charles Mauceri, James Semer, Stephen C. Moore, Marcelo F. Di Carli

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


Radionuclide myocardial perfusion imaging (MPI) plays a vital role in the evaluation and management of patients with coronary artery disease. However, because of a steep growth in MPI in the mid 2000s, concerns about inappropriate use of MPI and imaging-related radiation exposure increased. In response, the professional societies developed appropriate-use criteria for MPI. Simultaneously, novel technology, image-reconstruction software for traditional scanners, and dedicated cardiac scanners emerged and facilitated the performance of MPI with low-dose and ultra-low-dose radiotracers. This paper provides a practical approach to performing low-radiation-dose MPI using traditional and novel technologies.

Original languageEnglish (US)
Pages (from-to)592-599
Number of pages8
JournalJournal of Nuclear Medicine
Issue number4
StatePublished - Apr 1 2015
Externally publishedYes


  • Low dose
  • Myocardial perfusion imaging
  • PET
  • Quality assurance
  • Radiation dose

ASJC Scopus subject areas

  • Medicine(all)


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