Approach to the adult kidney stone former

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Nephrolithiasis is a prevalent and costly condition with high recurrence rate. A medical evaluation to identify abnormalities responsible for nephrolithiasis and guide subsequent therapy has been advocated to reduce the risk of stone recurrence. The evaluation of kidney stone formers generally comprises an extensive medical history to identify metabolic, environmental, dietary, and/or genetic factors contributing to stone formation. Imaging studies are utilized to evaluate and follow stone burden. Laboratory studies including stone composition analysis and serum and urinary chemistries are commonly obtained to further assess for any underlying systemic disorders, to detect environmental and metabolic processes contributing to stone disease, and to guide initial and follow-up dietary and pharmacological therapy. The nature and extent of such an evaluation is discussed in this review article.

Original languageEnglish (US)
Pages (from-to)38-49
Number of pages12
JournalClinical Reviews in Bone and Mineral Metabolism
Issue number1
StatePublished - Mar 2012


  • Evaluation
  • Hypercalciuria
  • Hyperoxaluria
  • Hypocitraturia
  • Kidney stones
  • Nephrolithiasis
  • Urolithiasis

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Endocrinology


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