Applications of magnetic nanoparticles in biomedicine

Carlos Bárcena; Amandeep K. Sra; Jinming Gao

doi:10.1007/978-0-387-85600-1_20

Applications of magnetic nanoparticles in biomedicine

Carlos Bárcena, Amandeep K. Sra, Jinming Gao

Research output: Chapter in Book/Report/Conference proceeding › Chapter

63 Scopus citations

Abstract

In recent years, magnetic nanoparticles have played an increasing role in biomedical applications and have been the subject of extensive research investigations. Physical properties, including nanoparticle size, composition, and surface chemistry, vary widely and influence their biological and pharmacological properties and, ultimately, their clinical applications. Among different magnetic nanoparticles, superparamagnetic iron oxide nanoparticles (SPIOs) were found nontoxic and used as magnetic resonance imaging (MRI) contrast agents, in molecular and cellular imaging applications. SPIOs are used in detection of liver metastases, metastatic lymph nodes, and inflammatory and/or neural degenerative diseases. In addition, drug delivery via magnetic targeting, hyperthermia, and labeling/∈tracking of stem cells have also been explored as potential therapeutic options.

Original language	English (US)
Title of host publication	Nanoscale Magnetic Materials and Applications
Publisher	Springer US
Pages	591-626
Number of pages	36
ISBN (Print)	9780387855981
DOIs	https://doi.org/10.1007/978-0-387-85600-1_20
State	Published - Dec 1 2009

ASJC Scopus subject areas

Engineering(all)

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AB - In recent years, magnetic nanoparticles have played an increasing role in biomedical applications and have been the subject of extensive research investigations. Physical properties, including nanoparticle size, composition, and surface chemistry, vary widely and influence their biological and pharmacological properties and, ultimately, their clinical applications. Among different magnetic nanoparticles, superparamagnetic iron oxide nanoparticles (SPIOs) were found nontoxic and used as magnetic resonance imaging (MRI) contrast agents, in molecular and cellular imaging applications. SPIOs are used in detection of liver metastases, metastatic lymph nodes, and inflammatory and/or neural degenerative diseases. In addition, drug delivery via magnetic targeting, hyperthermia, and labeling/∈tracking of stem cells have also been explored as potential therapeutic options.

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Applications of magnetic nanoparticles in biomedicine

Abstract

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