Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Chris A. Rees; Andrea T. Cruz; Stephen B. Freedman; Prashant Mahajan; Neil G. Uspal; Pamela Okada; Paul L. Aronson; Amy D. Thompson; Paul T. Ishimine; Suzanne M. Schmidt; Nathan Kuppermann; Lise E. Nigrovic

doi:10.1093/jpids/piy126

Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Chris A. Rees, Andrea T. Cruz, Stephen B. Freedman, Prashant Mahajan, Neil G. Uspal, Pamela Okada, Paul L. Aronson, Amy D. Thompson, Paul T. Ishimine, Suzanne M. Schmidt, Nathan Kuppermann, Lise E. Nigrovic

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.

Original language	English (US)
Pages (from-to)	559-562
Number of pages	4
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	8
Issue number	6
DOIs	https://doi.org/10.1093/jpids/piy126
State	Published - Dec 1 2019

Keywords

bacterial meningitis score
infants
sensitivity
specificity

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Infectious Diseases

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10.1093/jpids/piy126

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Rees, C. A., Cruz, A. T., Freedman, S. B., Mahajan, P., Uspal, N. G., Okada, P., Aronson, P. L., Thompson, A. D., Ishimine, P. T., Schmidt, S. M., Kuppermann, N., & Nigrovic, L. E. (2019). Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days. Journal of the Pediatric Infectious Diseases Society, 8(6), 559-562. https://doi.org/10.1093/jpids/piy126

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abstract = "In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.",

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note = "Publisher Copyright: {\textcopyright} 2018 The Author(s) 2018. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved.",

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AU - Rees, Chris A.

AU - Cruz, Andrea T.

AU - Freedman, Stephen B.

AU - Mahajan, Prashant

AU - Uspal, Neil G.

AU - Okada, Pamela

AU - Aronson, Paul L.

AU - Thompson, Amy D.

AU - Ishimine, Paul T.

AU - Schmidt, Suzanne M.

AU - Kuppermann, Nathan

AU - Nigrovic, Lise E.

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AB - In 4292 infants aged ≤60 days with cerebrospinal fluid (CSF) pleocytosis, the bacterial meningitis score had excellent sensitivity (121 of 121 [100.0%] [95% confidence interval, 96.5%-100.0%]) but low specificity (66 of 4171 [1.6%] [95% confidence interval, 1.3%-2.0%]) and therefore should not be applied clinically to infants in this age group.

KW - bacterial meningitis score

KW - infants

KW - sensitivity

KW - specificity

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Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days

Abstract

Keywords

ASJC Scopus subject areas

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