Apparent inadequacy of L-dopa stimulation as a clinical test of growth hormone release

C. Gómez-Sánchez; Norman M Kaplan

doi:10.1210/jcem-34-6-1105

Apparent inadequacy of L-dopa stimulation as a clinical test of growth hormone release

C. Gómez-Sánchez, Norman M Kaplan

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Abstract

The use of a single, oral, 500-mg dose of L-dopa has been compared to the arginineinsulin test as a stimulus for growth hormone (hGH) release in 15 patients. Whereas L-dopa induced a significant rise in hGH in 5 of 6 normals, it failed to do so in all 3 obese subjects, one patient with short stature and one with an enlarged sella, all of whom responded to arginineinsulin. The response to L-dopa in 2 hypothyroid patients was blunted. The hGH response to L-dopa appears to have limited usefulness in the clinical assessment of pituitary function.

Original language	English (US)
Pages (from-to)	1105-1107
Number of pages	3
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	34
Issue number	6
DOIs	https://doi.org/10.1210/jcem-34-6-1105
State	Published - Jan 1 1972

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

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10.1210/jcem-34-6-1105

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Apparent inadequacy of L-dopa stimulation as a clinical test of growth hormone release

Abstract

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