Antiphospholipid syndrome

Research output: Chapter in Book/Report/Conference proceedingChapter


The antiphospholipid syndrome (APS) is a disorder that is characterized by the presence of antibodies directed against phospholipid moieties in conjunction with venous and/or arterial thromboembolic events and/or obstetrical complications. There are other associated features including but not limited to seizures, thrombocytopenia and autoimmune hemolytic anemia, livedo reticularis, and renal disease. Rare complications include the catastrophic APS in which multiple clotting events occur simultaneously or in rapid succession. The antiphospholipid antibody syndrome can be seen by itself; primary APS, or in conjunction with other diseases such as systemic lupus erythematosus (SLE); secondary APS. This chapter will discuss the clinical manifestations and the management of the APS.

Original languageEnglish (US)
Title of host publicationLupus Erythematosus
Subtitle of host publicationClinical Evaluation and Treatment
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781461411895
ISBN (Print)1461411882, 9781461411888
StatePublished - Sep 1 2012

ASJC Scopus subject areas

  • General Medicine


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