Antimicrobial agents in pediatrics.

M. M. Mustafa, G. H. McCracken

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


For proper use of antimicrobial agents in infants and children, special precautions should be taken. These include knowledge of the pharmacokinetic properties of these agents, especially in neonates, and of host factors related to gestational and chronological ages of the patient. Failure to recognize such factors can result in either lack of therapeutic response of drug-related adverse effects. In this article, special aspects of the pharmacokinetics of antibiotics and the clinical pharmacology and indications for use of the beta-lactam antibiotics in infants and children are presented.

Original languageEnglish (US)
Pages (from-to)491-506
Number of pages16
JournalInfectious disease clinics of North America
Issue number3
StatePublished - Sep 1 1989

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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