TY - JOUR
T1 - Anthropometric features and cardiovascular risk in young Latin Americans with type 2 diabetes mellitus
AU - Avilés-Santa, Larissa
AU - Salinas, Karin
AU - Huet, Beverley A
AU - Raskin, Philip
N1 - Funding Information:
This project was sponsored in part by the National Institutes of Diabetes, Digestive and Kidney Diseases, K08 award DK02606, and by and the National Institutes for General Clinical Research Centers M01-RR00633.
PY - 2006
Y1 - 2006
N2 - Objective: The purpose of this study is to compare score systems used to estimate the risk for cardiovascular disease (CVD) in young patients with poorly controlled type 2 diabetes. Methods: Fifty-seven Latin American patients with type 2 diabetes, between the ages 18 and 45 years, were screened to participate in a clinical research study evaluating the effects of intensive insulin therapy on both traditional and nontraditional CVD risk factors. All women were premenopausal and had regular menstrual periods. Baseline reviews of cardiovascular (CV) risk scores, personal history, physical examination, and laboratory screening were performed. The Framingham Study Score system and the presence of features of the metabolic syndrome (MSyn) were recorded and compared. Results: Both genders had a comparable number of features of the MSyn, whereas according to the Framingham Score System, men had a slightly higher risk of CVD. Conclusions: The Framingham Score system is not an accurate device to estimate risk of CVD in premenopausal women with type 2 diabetes mellitus, who otherwise have a multiple features of the MSyn. If used to estimate risk of CVD, the Framingham score system could underestimate the risk of CVD in both young men and women with type 2 diabetes mellitus.
AB - Objective: The purpose of this study is to compare score systems used to estimate the risk for cardiovascular disease (CVD) in young patients with poorly controlled type 2 diabetes. Methods: Fifty-seven Latin American patients with type 2 diabetes, between the ages 18 and 45 years, were screened to participate in a clinical research study evaluating the effects of intensive insulin therapy on both traditional and nontraditional CVD risk factors. All women were premenopausal and had regular menstrual periods. Baseline reviews of cardiovascular (CV) risk scores, personal history, physical examination, and laboratory screening were performed. The Framingham Study Score system and the presence of features of the metabolic syndrome (MSyn) were recorded and compared. Results: Both genders had a comparable number of features of the MSyn, whereas according to the Framingham Score System, men had a slightly higher risk of CVD. Conclusions: The Framingham Score system is not an accurate device to estimate risk of CVD in premenopausal women with type 2 diabetes mellitus, who otherwise have a multiple features of the MSyn. If used to estimate risk of CVD, the Framingham score system could underestimate the risk of CVD in both young men and women with type 2 diabetes mellitus.
KW - Cardiovascular risks
KW - Central obesity
KW - Latinos
KW - Premenopausal women
KW - Type 2 diabetes mellitus
KW - Waist circumference
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U2 - 10.1016/j.jdiacomp.2005.09.001
DO - 10.1016/j.jdiacomp.2005.09.001
M3 - Article
C2 - 16504834
AN - SCOPUS:33644521731
SN - 1056-8727
VL - 20
SP - 69
EP - 74
JO - Journal of Diabetes and Its Complications
JF - Journal of Diabetes and Its Complications
IS - 2
ER -