An x-ray computed tomography/positron emission tomography system designed specifically for breast imaging

John M. Boone, Kai Yang, George W. Burkett, Nathan J. Packard, Shih Ying Huang, Spencer Bowen, Ramsey D. Badawi, Karen K. Lindfors

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Mammography has served the population of women who are at-risk for breast cancer well over the past 30 years. While mammography has undergone a number of changes as digital detector technology has advanced, other modalities such as computed tomography have experienced technological sophistication over this same time frame as well. The advent of large field of view flat panel detector systems enable the development of breast CT and several other niche CT applications, which rely on cone beam geometry. The breast, it turns out, is well suited to cone beam CT imaging because the lack of bones reduces artifacts, and the natural tapering of the breast anteriorly reduces the x-ray path lengths through the breast at large cone angle, reducing cone beam artifacts as well. We are in the process of designing a third prototype system which will enable the use of breast CT for image guided interventional procedures. This system will have several copies fabricated so that several breast CT scanners can be used in a multi-institutional clinical trial to better understand the role that this technology can bring to breast imaging.

Original languageEnglish (US)
Pages (from-to)29-43
Number of pages15
JournalTechnology in Cancer Research and Treatment
Issue number1
StatePublished - Feb 2010
Externally publishedYes


  • Breast cancer
  • Computed tomography
  • Diagnostic imaging
  • Equipment
  • Positron emission tomography
  • Radiation dose

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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