An unusually “complex” glomerulonephritis

Gabriela Martinez-Zayas, Daniel Savino, Sumit Kumar, Kathryn H. Dao

Research output: Contribution to journalArticlepeer-review


A 53-year-old man with granulomatosis with polyangiitis presented with fever and acute kidney injury with nephrotic-range proteinuria following the second dose of the mRNA COVID-19 vaccine. Renal biopsy revealed an unexpected immune complex-glomerulonephritis (IC-GN) without vasculitis. Further workup found the patient to have HIV that was unmasked following the treatment of IC-GN. This case report explores the possible relationship between COVID-19 vaccines and the immune response in the setting of chronic HIV.

Original languageEnglish (US)
Pages (from-to)531-533
Number of pages3
JournalBaylor University Medical Center Proceedings
Issue number4
StatePublished - 2022


  • COVID vaccine
  • glomerulonephritis
  • granulomatosis with polyangiitis
  • human immunodeficiency virus
  • immune complexes
  • type III hypersensitivity

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'An unusually “complex” glomerulonephritis'. Together they form a unique fingerprint.

Cite this