TY - JOUR
T1 - An unusual variant of congenital dyserythropoietic anaemia with mild maternal and lethal fetal disease
AU - Roberts, D. J.
AU - Nadel, A.
AU - Lage, J.
AU - Rutherford, C. J.
PY - 1993/7
Y1 - 1993/7
N2 - Summary. An unusual variant of congenital dyserythropoietic anaemia is described presenting as mild haemolytic anaemia with multinucleated erythroblasts in the marrow of the proband. The outcome of her non‐consanguineous pregnancy was a third trimester, in utero, fetal demise. The hydropic fetus had dyserythropoiesis with circulating multi‐nucleated erythroblasts, and haemosiderosis. Re‐evaluation of the proband revealed a variant of congenital dyserythropoietic anaemia with an inheritance pattern, and with morphological, serological and biochemical features which are not consistent with any of the three described variants of congenital dyserythropoietic anaemias.
AB - Summary. An unusual variant of congenital dyserythropoietic anaemia is described presenting as mild haemolytic anaemia with multinucleated erythroblasts in the marrow of the proband. The outcome of her non‐consanguineous pregnancy was a third trimester, in utero, fetal demise. The hydropic fetus had dyserythropoiesis with circulating multi‐nucleated erythroblasts, and haemosiderosis. Re‐evaluation of the proband revealed a variant of congenital dyserythropoietic anaemia with an inheritance pattern, and with morphological, serological and biochemical features which are not consistent with any of the three described variants of congenital dyserythropoietic anaemias.
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U2 - 10.1111/j.1365-2141.1993.tb03119.x
DO - 10.1111/j.1365-2141.1993.tb03119.x
M3 - Article
C2 - 8217810
AN - SCOPUS:0027320705
SN - 0007-1048
VL - 84
SP - 549
EP - 551
JO - British Journal of Haematology
JF - British Journal of Haematology
IS - 3
ER -