An enzyme that catalyzes hydrolysis of fructose-2,6-bisphosphate

Eisuke Furuya, Motoko Yokoyama, Kosaku Uyeda

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The enzyme which catalyzes the hydrolysis of fructose-2,6-P2 has been partially purified from rat liver. The product has been identified as fructose-6-P. The enzyme requires Mg++, and the K0.5 for fructose-2, 6-P2 varies from 25 - 100 μM, depending upon the preparation. After treatment with cAMP dependent protein kinase the enzyme is activated and the K0.5 for the substrate is lowered to 7 μM.

Original languageEnglish (US)
Pages (from-to)264-270
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number1
StatePublished - Mar 15 1982

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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