TY - JOUR
T1 - An Economic Analysis of Early and Late Complications After Adult Spinal Deformity Correction
AU - Williamson, Tyler K.
AU - Owusu-Sarpong, Stephane
AU - Imbo, Bailey
AU - Krol, Oscar
AU - Tretiakov, Peter
AU - Joujon-Roche, Rachel
AU - Ahmad, Salman
AU - Bennett-Caso, Claudia
AU - Schoenfeld, Andrew J.
AU - Lebovic, Jordan
AU - Vira, Shaleen
AU - Diebo, Bassel
AU - Lafage, Renaud
AU - Lafage, Virginie
AU - Passias, Peter G.
N1 - Funding Information:
1The paper is dedicated to J. L. Dong on the occasion of his 62nd birthday. 2This work was supported by the National Natural Science Foundation of P.R. China. The author is grateful to the referees for valuable comments and suggestions which greatly improved the original paper. The author also thanks Professor G. H. Tian for helpful discussions on topological properties of cones. 3Associate Professor, Department of Applied Mathematics, Jilin University of Technology, Changchun, P.R. China. Ph.D. student of Department of Mathematics, City University of Hong Kong.
Publisher Copyright:
© The Author(s) 2022.
PY - 2022
Y1 - 2022
N2 - Study design/setting: Retrospective cohort. Objective: Adult spinal deformity (ASD) corrective surgery is often a highly invasive procedure portending patients to both immediate and long-term complications. Therefore, we sought to compare the economic impact of certain complications before and after 2 years. Methods: ASD patients with minimum 3-year data included. Complication groups were defined as follows: any complication, major, medical, mechanical, radiographic, and reoperation. Complications stratified by occurrence before or after 2 years postoperatively. Published methods converted ODI to SF-6D to QALYs. Cost was calculated using CMS.gov definitions. Marginalized means for utility gained and cost-per-QALY were calculated via ANCOVA controlling for significant confounders. Results: 244 patients included. Before 2Y, complication rates: 76% ≥1 complication, 18% major, 26% required reoperation. After 2Y, complication rates: 32% ≥1 complication, 4% major, 2.5% required reoperation. Major complications after 2 years had worse cost-utility (.320 vs.441, P =.1). Patients suffering mechanical complications accrued the highest overall cost ($130,482.22), followed by infection and PJF for complications before 2 years. Patients suffering a mechanical complication after 2 years had lower cost-utility ($109,197.71 vs $130,482.22, P =.041). Patients developing PJF after 2 years accrued a better cost-utility ($77,227.84 vs $96,873.57; P =.038), compared to PJF before 2 years. Conclusion: Mechanical complications had the single greatest impact on cost-utility after adult spinal deformity surgery, but less so after 2 years. Understanding the cost-utility of specific interventions at certain timepoints may mitigate economic burden and prophylactic efforts should strategically be made against early mechanical complications.
AB - Study design/setting: Retrospective cohort. Objective: Adult spinal deformity (ASD) corrective surgery is often a highly invasive procedure portending patients to both immediate and long-term complications. Therefore, we sought to compare the economic impact of certain complications before and after 2 years. Methods: ASD patients with minimum 3-year data included. Complication groups were defined as follows: any complication, major, medical, mechanical, radiographic, and reoperation. Complications stratified by occurrence before or after 2 years postoperatively. Published methods converted ODI to SF-6D to QALYs. Cost was calculated using CMS.gov definitions. Marginalized means for utility gained and cost-per-QALY were calculated via ANCOVA controlling for significant confounders. Results: 244 patients included. Before 2Y, complication rates: 76% ≥1 complication, 18% major, 26% required reoperation. After 2Y, complication rates: 32% ≥1 complication, 4% major, 2.5% required reoperation. Major complications after 2 years had worse cost-utility (.320 vs.441, P =.1). Patients suffering mechanical complications accrued the highest overall cost ($130,482.22), followed by infection and PJF for complications before 2 years. Patients suffering a mechanical complication after 2 years had lower cost-utility ($109,197.71 vs $130,482.22, P =.041). Patients developing PJF after 2 years accrued a better cost-utility ($77,227.84 vs $96,873.57; P =.038), compared to PJF before 2 years. Conclusion: Mechanical complications had the single greatest impact on cost-utility after adult spinal deformity surgery, but less so after 2 years. Understanding the cost-utility of specific interventions at certain timepoints may mitigate economic burden and prophylactic efforts should strategically be made against early mechanical complications.
KW - adult spinal deformity
KW - complications
KW - cost-utility
KW - mechanical failure
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U2 - 10.1177/21925682221122762
DO - 10.1177/21925682221122762
M3 - Article
C2 - 36134677
AN - SCOPUS:85139028202
SN - 2192-5682
JO - Global Spine Journal
JF - Global Spine Journal
ER -