Amino acids regulate mTORC1 by an obligate two-step mechanism

Medicine & Life Sciences

• Mechanistic Target of Rapamycin Complex 1 100%
• Amino Acids 55%
• Aminoacylation 12%
• Isoleucine 11%
• Asparagine 11%
• Tuberous Sclerosis 10%
• Valine 10%
• Threonine 9%
• Proline 9%
• Glutamine 9%
• Methionine 9%
• Leucine 9%
• Lysosomes 9%
• Alanine 8%
• Glycine 8%
• Nutritional Status 8%
• Serine 8%
• Cysteine 8%
• Duration of Therapy 8%
• Arginine 8%
• Glutamic Acid 7%
• Intercellular Signaling Peptides and Proteins 7%
• Growth 4%
• Proteins 3%

Chemical Compounds

• Acid 27%
• L-Asparagine 12%
• L-Isoleucine 11%
• L-Glutamine 11%
• L-Threonine 11%
• L-Methionine 11%
• L-Valine 10%
• L-Serine 10%
• L-Leucine 10%
• L-Glutamic Acid 10%
• L-Arginine 10%
• L-Proline 10%
• L-Alanine 9%
• Sensitizing 9%
• L-Cysteine 9%
• Growth Factor 9%
• Energy 3%
• Protein 3%