ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM.

L. King-Breeding; M. S. Munro; R. C. Eberhart

ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM.

L. King-Breeding, M. S. Munro, R. C. Eberhart

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have shown that C//1//8 alkylation of polyurethane sheets and tubes selectively increases the affinities of these materials for albumin, in vitro and in vivo. We have also demonstrated a correlation between the enhancement of albumin affinity by this process and improved thromboresistance. In this study we extend the alkylation technique to open cell polyurethane foams of high porosity and pore size, such as are used in blood filtration devices. We report the enhancement of the albumin affinity of these materials by this technique, both with and without Antifoam A pretreatment.

Original language	English (US)
Title of host publication	Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors	James M. Anderson
Place of Publication	San Antonio, TX, USA
Publisher	Soc for Biomaterials
Pages	303
Number of pages	1
Volume	7
State	Published - 1984

ASJC Scopus subject areas

Materials Science(all)

Cite this

ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM. / King-Breeding, L.; Munro, M. S.; Eberhart, R. C.
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. ed. / James M. Anderson. Vol. 7 San Antonio, TX, USA: Soc for Biomaterials, 1984. p. 303.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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year = "1984",

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AU - Munro, M. S.

AU - Eberhart, R. C.

PY - 1984

Y1 - 1984

N2 - We have shown that C//1//8 alkylation of polyurethane sheets and tubes selectively increases the affinities of these materials for albumin, in vitro and in vivo. We have also demonstrated a correlation between the enhancement of albumin affinity by this process and improved thromboresistance. In this study we extend the alkylation technique to open cell polyurethane foams of high porosity and pore size, such as are used in blood filtration devices. We report the enhancement of the albumin affinity of these materials by this technique, both with and without Antifoam A pretreatment.

AB - We have shown that C//1//8 alkylation of polyurethane sheets and tubes selectively increases the affinities of these materials for albumin, in vitro and in vivo. We have also demonstrated a correlation between the enhancement of albumin affinity by this process and improved thromboresistance. In this study we extend the alkylation technique to open cell polyurethane foams of high porosity and pore size, such as are used in blood filtration devices. We report the enhancement of the albumin affinity of these materials by this technique, both with and without Antifoam A pretreatment.

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M3 - Conference contribution

AN - SCOPUS:0021563218

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BT - Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium

A2 - Anderson, James M.

PB - Soc for Biomaterials

CY - San Antonio, TX, USA

ER -

ALBUMIN UPTAKE ON C//1//8 ALKYLATED POLYURETHANE FOAM.

Abstract

ASJC Scopus subject areas

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