Aiolos and Lymphocyte Mimicry in Lung Cancer

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7 Scopus citations


Aggressive carcinomas tend to adopt behaviors normally restricted to lymphocytes, including anchorage-independent mobilization, response to chemokines, and modulation of local inflammatory conditions. In a recent study we identified the lymphocyte-restricted chromatin regulator Aiolos as an epigenetic driver of lymphocyte mimicry in lung cancer that links immune cell development to metastatic behavior.

Original languageEnglish (US)
Article numbere29912
JournalMolecular and Cellular Oncology
Issue number1
StatePublished - Jan 1 2014


  • Aiolos
  • IKZF3
  • Ikaros
  • Shc
  • anchorage independence
  • anoikis
  • lung cancer
  • lymphocyte
  • p66Shc

ASJC Scopus subject areas

  • Molecular Medicine
  • Cancer Research


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