Advanced nanomaterials: Promises for improved dental tissue regeneration

Janet R. Xavier, Prachi Desai, Venu Gopal Varanasi, Ibtisam Al-Hashimi, Akhilesh K. Gaharwar

Research output: Chapter in Book/Report/Conference proceedingChapter

16 Scopus citations


Nanotechnology is emerging as an interdisciplinary field that is undergoing rapid development and has become a powerful tool or various biomedical applications such as tissue regeneration, drug delivery, biosensors, gene transfection, and imaging. anomaterial- based design is able to mimic some of the mechanical and structural properties of native tissue and can promote iointegration. Ceramic-, metal-, and carbon-based nanoparticles possess unique physical, chemical, and biological characteristics due to the high surface- to-volume ratio. A range of synthetic nanoparticles such as hydroxyapatite, bioglass, titanium, irconia, and silver nanoparticles are proposed for dental restoration due to their unique bioactive characteristic. This review ocuses on the most recent development in the field of nanomaterials with emphasis on dental tissue engineering that provides an nspiration for the development of such advanced biomaterials. In particular, we discuss synthesis and fabrication of bioactive nanomaterials, examine their current limitations, and conclude with future directions in designing more advanced nanomaterials.

Original languageEnglish (US)
Title of host publicationNanotechnology in Endodontics
Subtitle of host publicationCurrent and Potential Clinical Applications
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783319135755
ISBN (Print)9783319135748
StatePublished - Jan 1 2015


  • Bioactivity
  • Biomedical applications
  • Dental tissue engineering
  • Drug delivery
  • Nanocomposites
  • Nanomaterials

ASJC Scopus subject areas

  • Dentistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)


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