Abstract
Pseudobulbar effect is a condition characterized by uncontrollable episodes of inappropriate laughing or crying that are disproportionate and discordant to the situation at hand. We report on a 16-year-old woman presenting with acute pathological laughter in the context of CNS demyelinating disease. Brain MRI scans fortuitously obtained before and after the onset of this symptom demonstrated acute gadolinium-enhancing lesions in the cerebral peduncles. The etiology of this condition remains theoretical; however, the results here provide further insights into the pathways of emotional control.
Original language | English (US) |
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Pages (from-to) | 1389-1390 |
Number of pages | 2 |
Journal | Movement Disorders |
Volume | 20 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2005 |
Keywords
- Inappropriate laughter
- Multiple sclerosis
- Pathological laughter
- Pseudobulbar affect
ASJC Scopus subject areas
- Neurology
- Clinical Neurology