Acute Ischemic Cerebrovascular Syndrome: Diagnostic Criteria

Chelsea S. Kidwell, Steven Warach

Research output: Contribution to journalReview articlepeer-review

135 Scopus citations


Background-Existing diagnostic classification systems for cerebrovascular disease are based primarily on clinical impression of temporal features, clinical syndrome, inferred localization, or ischemic mechanism. Diagnostic certainty of the ischemic pathology based on supportive or refuting laboratory or radiological evidence has been of secondary importance. Summary of Comment-Acute ischemic cerebrovascular syndrome (AICS) describes a spectrum of clinical presentations that share a similar underlying pathophysiology: cerebral ischemia. Diagnostic criteria for AICS incorporate prior classification systems and currently available information provided by neuroimaging and laboratory data to define 4 categories ranging from "definite AICS" to "not AICS," which define the degree of diagnostic certainty. Conclusions-Clinical trials testing new treatments for acute ischemic stroke or secondary stroke prevention should limit enrollment to patients with "definite" AICS whenever feasible.

Original languageEnglish (US)
Pages (from-to)2995-2998
Number of pages4
Issue number12
StatePublished - Dec 2003


  • Brain imaging
  • Classification
  • Diagnosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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