Acute effects of ethanol on motor performance and movement-related brain potentials

J. W. Rohrbaugh, J. M. Stapleton, H. W. Frowein, B. Adinoff, J. L. Varner, E. A. Lane, M. J. Eckardt, M. Linnoila

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The acute effects of ethanol on skilled motor functions were examined in male social drinkers, under four doses ranging from 0 (placebo) to 1.05 g/kg lean body weight. The movement entailed a forewarned choice transitive motion of the arm and hand, aimed at a flanking target. Performance measures disclosed only small effects of ethanol on speed and accuracy of movement. The simultaneously-recorded movement-related brain potentials disclosed decreased involvement of frontal and posterior brain areas, suggesting that ethanol disrupted the planning and regulation of movement despite the overall preservation of reaction speed.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalAdvances in Alcohol and Substance Abuse
Issue number3-4
StatePublished - Mar 1 1988

ASJC Scopus subject areas

  • Medicine (miscellaneous)


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