TY - JOUR
T1 - Acute effects of drug abuse in schizophrenic patients
T2 - Clinical observations and patients' self-reports
AU - Dixon, Lisa
AU - Haas, Gretchen
AU - Weiden, Peter
AU - Sweeney, John
AU - Frances, Allen
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 1990
Y1 - 1990
N2 - Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.
AB - Substance abuse among schizophrenic patients is an increasingly recognized clinical phenomenon. The authors review experimental and observed clinical effects of drug abuse and patients' subjective experiences of acute intoxication. Though drug abuse may exacerbate psychotic symptoms, abused drugs may also lead to transient symptom reduction in subgroups of schizophrenic patients. Some patients report feeling less dysphoric, less anxious, and more energetic while intoxicated. Models of the relationship of drug abuse and schizophrenia, particularly the self-medication hypothesis, are discussed in reference to these data.
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U2 - 10.1093/schbul/16.1.69
DO - 10.1093/schbul/16.1.69
M3 - Article
C2 - 2185536
AN - SCOPUS:0025373449
SN - 0586-7614
VL - 16
SP - 69
EP - 79
JO - Schizophrenia Bulletin
JF - Schizophrenia Bulletin
IS - 1
ER -