Actinomyces associated with persistent vaginal granulation tissue

Clifford Y. Wai, Mikio A. Nihira, Peter G. Drewes, Joe S. Chang, Momin T. Siddiqui, David L. Hemsell

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Background: We report a case of symptomatic actinomycosis associated with vaginal suture erosion and granulation tissue refractory to conservative management, in an outpatient setting. Case: Three months after total vaginal hysterectomy and uterosacral ligament vaginal vault suspension, a woman complained of painless, intermittent vaginal discharge and spotting. Despite cauterization of granulation tissue, vaginal spotting persisted for another month. On re-examination, braided polyester suture that was found underlying the granulation tissue was removed. Recurrent symptoms, together with a biopsy revealing actinomycetes, prompted a trial of oral penicillin VK. With persistent symptoms and discomfort during attempts in the outpatient clinic, the woman eventually required suture removal in the operating room. Her symptoms subsequently resolved without recurrence, and no further antibiotic treatment was required. Conclusions: Actinomyces may be associated with persistent granulation tissue and vault suspension suture material. In rare circumstances, when tissue debridement and suture removal in the clinic is unsatisfactory, surgical intervention in the operating room may be necessary. Ten days of antibiotic therapy alone did not eradicate the granulation tissue, and symptoms resolved only after complete removal of the underlying permanent suture.

Original languageEnglish (US)
Pages (from-to)53-55
Number of pages3
JournalInfectious Disease in Obstetrics and Gynecology
Issue number1
StatePublished - Mar 2005


  • Actinomycosis
  • Postoperative complications
  • Sulfur granules
  • Suture erosion

ASJC Scopus subject areas

  • Dermatology
  • Obstetrics and Gynecology
  • Infectious Diseases


Dive into the research topics of 'Actinomyces associated with persistent vaginal granulation tissue'. Together they form a unique fingerprint.

Cite this