Actinic keratoses: Differential diagnosis and treatment

John W J Barnaby, Angela R. Styles, Clay J. Cockerell

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Actinic keratoses are extremely common premalignant keratinocytic neoplastic lesions that develop primarily in fair-complexioned individuals during midlife or beyond. Genetic, occupational and other environmental factors predispose to the development of these lesions, Without treatment, a significant number may progress to fully developed neoplasms, especially squamous cell carcinoma. over a period of 20 to 50 years. The multistep theory of carcinogenesis is helpful in understanding the pathogenesis and progression of this important and highly prevalent lesion.

Original languageEnglish (US)
Pages (from-to)186-205
Number of pages20
JournalDrugs and Aging
Issue number3
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Pharmacology (medical)


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