Actinic keratoses are extremely common premalignant keratinocytic neoplastic lesions that develop primarily in fair-complexioned individuals during midlife or beyond. Genetic, occupational and other environmental factors predispose to the development of these lesions, Without treatment, a significant number may progress to fully developed neoplasms, especially squamous cell carcinoma. over a period of 20 to 50 years. The multistep theory of carcinogenesis is helpful in understanding the pathogenesis and progression of this important and highly prevalent lesion.
|Original language||English (US)|
|Number of pages||20|
|Journal||Drugs and Aging|
|State||Published - Jan 1 1997|
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Pharmacology (medical)