Abstract
Actinic keratoses are extremely common premalignant keratinocytic neoplastic lesions that develop primarily in fair-complexioned individuals during midlife or beyond. Genetic, occupational and other environmental factors predispose to the development of these lesions, Without treatment, a significant number may progress to fully developed neoplasms, especially squamous cell carcinoma. over a period of 20 to 50 years. The multistep theory of carcinogenesis is helpful in understanding the pathogenesis and progression of this important and highly prevalent lesion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 186-205 |
| Number of pages | 20 |
| Journal | Drugs and Aging |
| Volume | 11 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1997 |
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Pharmacology (medical)