TY - JOUR
T1 - Acanthamoeba keratitis associated with soft contact lenses
AU - Moore, M. B.
AU - McCulley, J. P.
AU - Luckenbach, M.
AU - Gelender, H.
AU - Newton, C.
AU - McDonald, M. B.
AU - Visvesvara, G. S.
N1 - Funding Information:
From the Department of Ophthalmology, University of Texas Health Science Center, Dallas, Texas (Drs. Moore, McCulley, Luckenbach and Gelender); the Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans (Drs. Moore, Newton, and McDonald); and the Centers for Disease Control, Atlanta, Georgia (Dr. Visvesvara). This study was supported in part by grants EY05800 (Dr. Moore), EY02302 and EY03650 (Dr. McCulley), and EY05803 (Dr. Newton) from the National Eye Institute and a grant from Research to Prevent Blindness, Inc., New York, New York (Dr. McCulley).
PY - 1985/9/15
Y1 - 1985/9/15
N2 - Three patients (a 13-year-old girl, a 25-year-old man, and a 22-year-old woman) who used daily-wear soft contact lenses, sterilized with saline made from distilled water and salt tablets, developed Acanthamoeba keratitis. Acanthamoeba was cultured from the contact lens solution of one patient. This patient, in whom the diagnosis was made by corneal biopsy early in the clinical course, was successfully treated with topical neomycin-polymyxin, miconazole, and propamidine isethionate. The other two patients underwent penetrating keratoplasty. One of these patients, who received a graft early in the clinical course, developed a recurrence of disease in the graft, whereas the other, who received the graft 18 months after the initial symptoms, has maintained a clear corneal transplant with useful vision.
AB - Three patients (a 13-year-old girl, a 25-year-old man, and a 22-year-old woman) who used daily-wear soft contact lenses, sterilized with saline made from distilled water and salt tablets, developed Acanthamoeba keratitis. Acanthamoeba was cultured from the contact lens solution of one patient. This patient, in whom the diagnosis was made by corneal biopsy early in the clinical course, was successfully treated with topical neomycin-polymyxin, miconazole, and propamidine isethionate. The other two patients underwent penetrating keratoplasty. One of these patients, who received a graft early in the clinical course, developed a recurrence of disease in the graft, whereas the other, who received the graft 18 months after the initial symptoms, has maintained a clear corneal transplant with useful vision.
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U2 - 10.1016/0002-9394(85)90500-8
DO - 10.1016/0002-9394(85)90500-8
M3 - Article
C2 - 3898851
AN - SCOPUS:0021994708
SN - 0002-9394
VL - 100
SP - 396
EP - 403
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -