Acanthamoeba keratitis associated with soft contact lenses

M. B. Moore, J. P. McCulley, M. Luckenbach, H. Gelender, C. Newton, M. B. McDonald, G. S. Visvesvara

Research output: Contribution to journalArticlepeer-review

170 Scopus citations


Three patients (a 13-year-old girl, a 25-year-old man, and a 22-year-old woman) who used daily-wear soft contact lenses, sterilized with saline made from distilled water and salt tablets, developed Acanthamoeba keratitis. Acanthamoeba was cultured from the contact lens solution of one patient. This patient, in whom the diagnosis was made by corneal biopsy early in the clinical course, was successfully treated with topical neomycin-polymyxin, miconazole, and propamidine isethionate. The other two patients underwent penetrating keratoplasty. One of these patients, who received a graft early in the clinical course, developed a recurrence of disease in the graft, whereas the other, who received the graft 18 months after the initial symptoms, has maintained a clear corneal transplant with useful vision.

Original languageEnglish (US)
Pages (from-to)396-403
Number of pages8
JournalAmerican journal of ophthalmology
Issue number3
StatePublished - Sep 15 1985

ASJC Scopus subject areas

  • Ophthalmology


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