Abnormalities of T-cell receptor repertoire in CD4                         +                          regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity

Jared H. Rowe; Brian D. Stadinski; Lauren A. Henderson; Lisa Ott de Bruin; Ottavia Delmonte; Yu Nee Lee; M. Teresa de la Morena; Rakesh K. Goyal; Anthony Hayward; Chiung Hui Huang; Maria Kanariou; Alejandra King; Taco W. Kuijpers; Jian Yi Soh; Benedicte Neven; Jolan E. Walter; Eric S. Huseby

doi:10.1016/j.jaci.2017.08.001

Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity

Jared H. Rowe, Brian D. Stadinski, Lauren A. Henderson, Lisa Ott de Bruin, Ottavia Delmonte, Yu Nee Lee, M. Teresa de la Morena, Rakesh K. Goyal, Anthony Hayward, Chiung Hui Huang, Maria Kanariou, Alejandra King, Taco W. Kuijpers, Jian Yi Soh, Benedicte Neven, Jolan E. Walter, Eric S. Huseby

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Original language	English (US)
Pages (from-to)	1739-1743.e7
Journal	Journal of Allergy and Clinical Immunology
Volume	140
Issue number	6
DOIs	https://doi.org/10.1016/j.jaci.2017.08.001
State	Published - Dec 2017

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/j.jaci.2017.08.001

Cite this

Rowe, J. H., Stadinski, B. D., Henderson, L. A., de Bruin, L. O., Delmonte, O., Lee, Y. N., de la Morena, M. T., Goyal, R. K., Hayward, A., Huang, C. H., Kanariou, M., King, A., Kuijpers, T. W., Soh, J. Y., Neven, B., Walter, J. E., & Huseby, E. S. (2017). Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity. Journal of Allergy and Clinical Immunology, 140(6), 1739-1743.e7. https://doi.org/10.1016/j.jaci.2017.08.001

Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity. / Rowe, Jared H.; Stadinski, Brian D.; Henderson, Lauren A. et al.
In: Journal of Allergy and Clinical Immunology, Vol. 140, No. 6, 12.2017, p. 1739-1743.e7.

Research output: Contribution to journal › Article › peer-review

Rowe, JH, Stadinski, BD, Henderson, LA, de Bruin, LO, Delmonte, O, Lee, YN, de la Morena, MT, Goyal, RK, Hayward, A, Huang, CH, Kanariou, M, King, A, Kuijpers, TW, Soh, JY, Neven, B, Walter, JE & Huseby, ES 2017, 'Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity', Journal of Allergy and Clinical Immunology, vol. 140, no. 6, pp. 1739-1743.e7. https://doi.org/10.1016/j.jaci.2017.08.001

Rowe JH, Stadinski BD, Henderson LA, de Bruin LO, Delmonte O, Lee YN et al. Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity. Journal of Allergy and Clinical Immunology. 2017 Dec;140(6):1739-1743.e7. doi: 10.1016/j.jaci.2017.08.001

@article{829cd57d523846f8947cac2405a1055b,

title = "Abnormalities of T-cell receptor repertoire in CD4 + regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity",

author = "Rowe, {Jared H.} and Stadinski, {Brian D.} and Henderson, {Lauren A.} and {de Bruin}, {Lisa Ott} and Ottavia Delmonte and Lee, {Yu Nee} and {de la Morena}, {M. Teresa} and Goyal, {Rakesh K.} and Anthony Hayward and Huang, {Chiung Hui} and Maria Kanariou and Alejandra King and Kuijpers, {Taco W.} and Soh, {Jian Yi} and Benedicte Neven and Walter, {Jolan E.} and Huseby, {Eric S.}",

note = "Funding Information: Disclosure of potential conflict of interest: J. H. Rowe is employed by Dana Farber Cancer Institute. B. D. Stadinski has received grants from the National Institutes of Health (grant nos. U19 AI109858-01, R01 DK095077-05, and R01 AR071269-02) and is employed by the University of Massachusetts Medical School. Y. N. Lee has received travel support from the Jeffrey Modell Foundation. M. T. de la Morena has received a grant from the National Institutes of Health (grant no. 5R01AI114523). A. Hayward is employed by Brown University and has received grants from the National Institutes of Health. C. H. Huang is employed by the National University of Singapore. J. E. Walter has consultant arrangements with and has received payment for lectures from Shire and CSL-Behring, has received a grant from the National Institute of Allergy and Infectious Diseases (grant no. K08AI103035), and a grant from the National Institutes of Health (grant no. 5R01AI100887). E. S. Huseby has received a grant from the National Institutes of Health. L. D. Notarangelo has received a grant from the National Institute of Allergy and Infectious Disease; has board memberships with the Journal of Clinical Immunology , Clinical Immunology , and Frontiers in Immunology ; and has received royalties from UpToDate. The rest of the authors declare that they have no relevant conflicts of interest. Letter to the Editor Funding Information: This work was supported by grants from the National Institute of Allergy and Infectious Diseases , National Institutes of Health (grant nos. 2R01AI100887 and 2U54AI082973 ) and by the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health (protocol 16-I-N139). ",

year = "2017",

month = dec,

doi = "10.1016/j.jaci.2017.08.001",

language = "English (US)",

volume = "140",

pages = "1739--1743.e7",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

number = "6",

}

TY - JOUR

T1 - Abnormalities of T-cell receptor repertoire in CD4 + regulatory and conventional T cells in patients with RAG mutations

T2 - Implications for autoimmunity

AU - Rowe, Jared H.

AU - Stadinski, Brian D.

AU - Henderson, Lauren A.

AU - de Bruin, Lisa Ott

AU - Delmonte, Ottavia

AU - Lee, Yu Nee

AU - de la Morena, M. Teresa

AU - Goyal, Rakesh K.

AU - Hayward, Anthony

AU - Huang, Chiung Hui

AU - Kanariou, Maria

AU - King, Alejandra

AU - Kuijpers, Taco W.

AU - Soh, Jian Yi

AU - Neven, Benedicte

AU - Walter, Jolan E.

AU - Huseby, Eric S.

N1 - Funding Information: Disclosure of potential conflict of interest: J. H. Rowe is employed by Dana Farber Cancer Institute. B. D. Stadinski has received grants from the National Institutes of Health (grant nos. U19 AI109858-01, R01 DK095077-05, and R01 AR071269-02) and is employed by the University of Massachusetts Medical School. Y. N. Lee has received travel support from the Jeffrey Modell Foundation. M. T. de la Morena has received a grant from the National Institutes of Health (grant no. 5R01AI114523). A. Hayward is employed by Brown University and has received grants from the National Institutes of Health. C. H. Huang is employed by the National University of Singapore. J. E. Walter has consultant arrangements with and has received payment for lectures from Shire and CSL-Behring, has received a grant from the National Institute of Allergy and Infectious Diseases (grant no. K08AI103035), and a grant from the National Institutes of Health (grant no. 5R01AI100887). E. S. Huseby has received a grant from the National Institutes of Health. L. D. Notarangelo has received a grant from the National Institute of Allergy and Infectious Disease; has board memberships with the Journal of Clinical Immunology , Clinical Immunology , and Frontiers in Immunology ; and has received royalties from UpToDate. The rest of the authors declare that they have no relevant conflicts of interest. Letter to the Editor Funding Information: This work was supported by grants from the National Institute of Allergy and Infectious Diseases , National Institutes of Health (grant nos. 2R01AI100887 and 2U54AI082973 ) and by the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health (protocol 16-I-N139).

PY - 2017/12

Y1 - 2017/12

UR - http://www.scopus.com/inward/record.url?scp=85030029307&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85030029307&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2017.08.001

DO - 10.1016/j.jaci.2017.08.001

M3 - Article

C2 - 28864286

AN - SCOPUS:85030029307

SN - 0091-6749

VL - 140

SP - 1739-1743.e7

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 6

ER -

Abnormalities of T-cell receptor repertoire in CD4 + regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this

Abnormalities of T-cell receptor repertoire in CD4 ⁺ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity