Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection

Tina Dewan Mahajan; Roderick Hooker; Lisa Maher; Geri Brown; Andreas Reimold

doi:10.1097/RHU.0b013e3181f4cd92

Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection

Tina Dewan Mahajan, Roderick Hooker, Lisa Maher, Geri Brown, Andreas Reimold

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.

Original language	English (US)
Pages (from-to)	332-334
Number of pages	3
Journal	Journal of Clinical Rheumatology
Volume	16
Issue number	7
DOIs	https://doi.org/10.1097/RHU.0b013e3181f4cd92
State	Published - Oct 1 2010

Keywords

Abatacept
hepatitis C infection
rheumatoid arthritis

ASJC Scopus subject areas

Rheumatology

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10.1097/RHU.0b013e3181f4cd92

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abstract = "Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.",

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AU - Brown, Geri

AU - Reimold, Andreas

PY - 2010/10/1

Y1 - 2010/10/1

N2 - Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.

AB - Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.

KW - Abatacept

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KW - rheumatoid arthritis

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Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection

Abstract

Keywords

ASJC Scopus subject areas

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