Abstract
The authors performed an open-label, rater-blinded, add-on study of sodium oxybate in 20 patients with ethanol-responsive myoclonus or essential tremor. Blinded ratings of videotaped examinations showed improvements in myoclonus at rest, stimulus-sensitive myoclonus, action myoclonus, functional performance, and postural and kinetic tremor. Tolerability was acceptable, and more than half of the patients chose to continue treatment after the trial. Double-blind placebo-controlled studies in these disorders are warranted.
Original language | English (US) |
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Pages (from-to) | 1967-1970 |
Number of pages | 4 |
Journal | Neurology |
Volume | 65 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2005 |
Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology