TY - JOUR
T1 - A Review of Current Keloid Management
T2 - Mainstay Monotherapies and Emerging Approaches
AU - Limmer, Emily E.
AU - Glass, Donald A.
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Commonly affecting those with skin of color, keloids are an aberrant wound response that leads to wound tissue expanding above and beyond the original cutaneous injury. Keloids are notoriously and particularly difficult to treat because of their tendency to recur after excision. The current standard of care is intralesional steroid (triamcinolone acetonide). However, because no therapy has yet proven to be fully curative, keloid treatments have expanded to include a number of options, from injections to multimodal approaches. This review details current treatment of keloids with injections (bleomycin, verapamil, hyaluronic acid and hyaluronidase, botulinum toxin, and collagenase), cryotherapy, laser, radiofrequency ablation, radiation, extracorporeal shockwave therapy, pentoxifylline, and dupilumab.
AB - Commonly affecting those with skin of color, keloids are an aberrant wound response that leads to wound tissue expanding above and beyond the original cutaneous injury. Keloids are notoriously and particularly difficult to treat because of their tendency to recur after excision. The current standard of care is intralesional steroid (triamcinolone acetonide). However, because no therapy has yet proven to be fully curative, keloid treatments have expanded to include a number of options, from injections to multimodal approaches. This review details current treatment of keloids with injections (bleomycin, verapamil, hyaluronic acid and hyaluronidase, botulinum toxin, and collagenase), cryotherapy, laser, radiofrequency ablation, radiation, extracorporeal shockwave therapy, pentoxifylline, and dupilumab.
KW - CO laser
KW - Cryotherapy
KW - Intralesional injection
KW - Keloid
KW - Multimodal approach
KW - Pulse dye laser
KW - Radiation
KW - Radiofrequency ablation
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=85088582130&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85088582130&partnerID=8YFLogxK
U2 - 10.1007/s13555-020-00427-2
DO - 10.1007/s13555-020-00427-2
M3 - Review article
C2 - 32705533
AN - SCOPUS:85088582130
SN - 2190-9172
VL - 10
SP - 931
EP - 948
JO - Dermatology and Therapy
JF - Dermatology and Therapy
IS - 5
ER -