TY - JOUR
T1 - A proof-of-concept trial of a community-based aerobic exercise program for individuals with traumatic brain injury
AU - Ding, Kan
AU - Tarumi Ph.D., Takashi
AU - Tomoto, Tsubasa
AU - Bell, Kathleen R.
AU - Madden, Christopher
AU - Dieppa, Marisara
AU - Cullum, C. Munro
AU - Zhang, Song
AU - Zhang, Rong
N1 - Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.
PY - 2021
Y1 - 2021
N2 - Objective: To assess the feasibility of conducting an aerobic exercise training study in a community setting for individuals with traumatic brain injury (TBI) Methods: This is a prospective, randomized, and controlled study. Nine participants (three moderate-to-severe and six mild TBI) were randomized to a community-based 3-month individualized aerobic exercise training program (AET). Seven participants (four moderate-to-severe, three mild TBI) were randomized to a stretching and toning program (SAT). Cardiorespiratory fitness (CRF) level was assessed with peak oxygen uptake (VO2peak) testing. Results: After 3 months of training, the AET trended toward improved VO2peak when compared with the SAT group (8% vs–4%, p = .059) with a large effect size of 1.27. Only 50% of participants in the AET group completed more than 70% of the assigned exercise sessions. No adverse events were reported. Both the AET and SAT groups reported small improvements in self-reported mood symptoms, including depression, anxiety, and anger. Conclusions: It is feasible to conduct an exercise training study and improve CRF for persons with TBI in community settings with structured exercise protocols. However, exploring methods to enhance adherence is crucial for future exercise clinical trials to improve brain health in this population.
AB - Objective: To assess the feasibility of conducting an aerobic exercise training study in a community setting for individuals with traumatic brain injury (TBI) Methods: This is a prospective, randomized, and controlled study. Nine participants (three moderate-to-severe and six mild TBI) were randomized to a community-based 3-month individualized aerobic exercise training program (AET). Seven participants (four moderate-to-severe, three mild TBI) were randomized to a stretching and toning program (SAT). Cardiorespiratory fitness (CRF) level was assessed with peak oxygen uptake (VO2peak) testing. Results: After 3 months of training, the AET trended toward improved VO2peak when compared with the SAT group (8% vs–4%, p = .059) with a large effect size of 1.27. Only 50% of participants in the AET group completed more than 70% of the assigned exercise sessions. No adverse events were reported. Both the AET and SAT groups reported small improvements in self-reported mood symptoms, including depression, anxiety, and anger. Conclusions: It is feasible to conduct an exercise training study and improve CRF for persons with TBI in community settings with structured exercise protocols. However, exploring methods to enhance adherence is crucial for future exercise clinical trials to improve brain health in this population.
KW - Traumatic brain injury
KW - aerobic exercise training
KW - cardiorespiratory fitness
KW - cognitive performance
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U2 - 10.1080/02699052.2020.1865569
DO - 10.1080/02699052.2020.1865569
M3 - Article
C2 - 33385308
AN - SCOPUS:85098639545
SN - 0269-9052
VL - 35
SP - 233
EP - 240
JO - Brain injury
JF - Brain injury
IS - 2
ER -