Abstract
A total of 44 women received a combination of ifosfamide (1.5 g/m2 daily x5) and cisplatin (50 mg/m2 on day 1 only) as first-line chemotherapy for recurrent or metastatic carcinoma of the cervix. In all, 12/42 (38%) evaluable patients responded, with the median duration of response being 7 months. Bone marrow and gastrointestinal toxicity were frequently severe. There were 3 septic death. Although cisplatin plus ifosfamide is an active combination against this disease, these results suggest that it is no more so than either drug used alone.
Original language | English (US) |
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Pages (from-to) | 52-54 |
Number of pages | 3 |
Journal | Cancer Chemotherapy and Pharmacology |
Volume | 27 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1990 |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Toxicology
- Pharmacology
- Cancer Research
- Pharmacology (medical)