Abstract
The results of dimethyl suberimidate cross-linking experiments demonstrate that histone H1 can be cross-linked quantitatively to the histone octamer of mononucleosomes to yield a histone nonamer. By combining our cross-linking procedure with two-dimensional electrophoretic techniques, we show further that it is possible to trace the nucleosomal origins of a spectrum of cross-linked chromatin products.
Original language | English (US) |
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Pages (from-to) | 4511-4515 |
Number of pages | 5 |
Journal | Journal of Biological Chemistry |
Volume | 255 |
Issue number | 10 |
State | Published - May 25 1980 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology