A new method for protein domain recognition

Z. Y. Xuan, L. J. Ling, R. S. Chen

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A fuzzy cluster method is presented to recognize protein domains. This algorithm can identify domains globally. A protein structure set was used to test the algorithm. Among 219 proteins, 66.7% yielded results that agreed with the reference definitions, 30.6% showed minor differences, and only 2.7% (six proteins) showed major differences with the reference. The new method is more than 20 times fast than previous algorithms.

Original languageEnglish (US)
Pages (from-to)7-16
Number of pages10
JournalEuropean Biophysics Journal
Issue number1
StatePublished - 2000
Externally publishedYes


  • Domain database
  • Fuzzy cluster analysis
  • Protein domain
  • Protein structure

ASJC Scopus subject areas

  • Biophysics


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