A new medication for treatment of dry mouth in Sjögren's syndrome.

I. al-Hashimi, S. E. Taylor

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Traditionally, treatment of dry mouth in SS is focused on palliative measures (using salivary substitutes). However, due to the dynamic nature of the oral cavity, the salivary substitute is removed from the mouth during swallowing. Therefore, the duration of effect of salivary substitutes is short. Another drawback is that salivary substitutes do not provide the protective roles of saliva. Effective treatment of dry mouth requires increasing salivary output. Gustatory stimulation of the salivary glands with sugar free gum and sugar free candies may be effective in inducing salivary output, however, they impose significant inconvenience on the patient which can compromise compliance. Pharmacological stimulants provide an alternative effective measure and improve compliance. Both Salagen and Evoxac are FDA approved salivary stimulants. They are effective, and safe given awareness of their indications, contraindications, potential adverse effects, and patient's tolerance.

Original languageEnglish (US)
Pages (from-to)262-266
Number of pages5
JournalTexas dental journal
Issue number3
StatePublished - Apr 2001

ASJC Scopus subject areas

  • Dentistry(all)


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