TY - JOUR
T1 - A multicenter study on childhood constipation and fecal incontinence
T2 - Effects on quality of life
AU - Kovacic, Katja
AU - Sood, Manu R.
AU - Mugie, Suzanne
AU - Di Lorenzo, Carlo
AU - Nurko, Samuel
AU - Heinz, Nicole
AU - Ponnambalam, Ananthasekar
AU - Beesley, Christina
AU - Sanghavi, Rina
AU - Silverman, Alan H.
N1 - Publisher Copyright:
Copyright © 2015 Elsevier Inc. All rights reserved.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Objective To describe the effects of childhood functional constipation compared with functional constipation plus fecal incontinence on quality of life, evaluating effects on physical, psychosocial, and family functioning. Study design This prospective, multicenter study collected data from 5 regional children's hospitals. Children meeting Rome III criteria for functional constipation were included. Parents completed the following 5 instruments: Pediatric Quality of Life Inventory (PedsQL), PedsQL-Family Impact Module, Functional Disability Inventory-Parent Version, Pediatric Inventory for Parents (PIP), and Pediatric Symptom Checklist-Parent Report. Results Families of 410 children aged 2-18 years (mean [SD], 7.8 [3.5] years; 52% male) were included. Children with functional constipation+fecal incontinence had worse quality of life than children with functional constipation alone (PedsQL Total Score, P ≤.03). Older children with functional constipation + fecal incontinence had lower quality of life than their younger counterparts (PedsQL Total Score, P ≤.047). Children with functional constipation+fecal incontinence had worse family functioning (PedsQL-Family Impact Module Total Score, P ≤.012), greater parental stress (PIP-F Total Score, P ≤.016; PIP-D Total Score, P ≤.013), and poorer psychosocial functioning (Pediatric Symptom Checklist Total Score, P ≤.003). There were no statistically significant between-group differences in physical functioning based on the functional Disability Inventory. Conclusion Fecal incontinence significantly decreases quality of life compared with functional constipation alone in children. Older children with functional constipation+fecal incontinence may be at particular risk. Strategies for early identification and treatment of constipation along with diagnosis and treatment of related adjustment difficulties may mitigate the negative impact of this highly prevalent condition.
AB - Objective To describe the effects of childhood functional constipation compared with functional constipation plus fecal incontinence on quality of life, evaluating effects on physical, psychosocial, and family functioning. Study design This prospective, multicenter study collected data from 5 regional children's hospitals. Children meeting Rome III criteria for functional constipation were included. Parents completed the following 5 instruments: Pediatric Quality of Life Inventory (PedsQL), PedsQL-Family Impact Module, Functional Disability Inventory-Parent Version, Pediatric Inventory for Parents (PIP), and Pediatric Symptom Checklist-Parent Report. Results Families of 410 children aged 2-18 years (mean [SD], 7.8 [3.5] years; 52% male) were included. Children with functional constipation+fecal incontinence had worse quality of life than children with functional constipation alone (PedsQL Total Score, P ≤.03). Older children with functional constipation + fecal incontinence had lower quality of life than their younger counterparts (PedsQL Total Score, P ≤.047). Children with functional constipation+fecal incontinence had worse family functioning (PedsQL-Family Impact Module Total Score, P ≤.012), greater parental stress (PIP-F Total Score, P ≤.016; PIP-D Total Score, P ≤.013), and poorer psychosocial functioning (Pediatric Symptom Checklist Total Score, P ≤.003). There were no statistically significant between-group differences in physical functioning based on the functional Disability Inventory. Conclusion Fecal incontinence significantly decreases quality of life compared with functional constipation alone in children. Older children with functional constipation+fecal incontinence may be at particular risk. Strategies for early identification and treatment of constipation along with diagnosis and treatment of related adjustment difficulties may mitigate the negative impact of this highly prevalent condition.
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U2 - 10.1016/j.jpeds.2015.03.016
DO - 10.1016/j.jpeds.2015.03.016
M3 - Article
C2 - 26008173
AN - SCOPUS:84930148039
SN - 0022-3476
VL - 166
SP - 1482-1487.e1
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 6
ER -