A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Errol C. Friedberg

doi:10.1016/j.dnarep.2015.12.003

A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Errol C. Friedberg

Research output: Contribution to journal › Comment/debate › peer-review

33 Scopus citations

Abstract

This article reviews the early history of the discovery of an DNA repair path way designated as base excision repair(BER),since in contrast to the enzyme-catalyzed removal of damaged bases from DNA as nucleotides [called nucleotide excision repair(NER)],BER involves the removal of damage dor in appropriate bases,such as the presence of uracil instead of thymine ,from DNA as free bases.

Original language	English (US)
Pages (from-to)	A35-A39
Journal	DNA repair
Volume	37
DOIs	https://doi.org/10.1016/j.dnarep.2015.12.003
State	Published - Jan 1 2016

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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10.1016/j.dnarep.2015.12.003

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abstract = "This article reviews the early history of the discovery of an DNA repair path way designated as base excision repair(BER),since in contrast to the enzyme-catalyzed removal of damaged bases from DNA as nucleotides [called nucleotide excision repair(NER)],BER involves the removal of damage dor in appropriate bases,such as the presence of uracil instead of thymine ,from DNA as free bases.",

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A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Abstract

ASJC Scopus subject areas

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