TY - GEN
T1 - A High-Performance Onboard Small Animal PET for Preclinical Radiotherapy Research
AU - Cheng, Xinyi
AU - Hu, Kun
AU - Yang, Dongxu
AU - Shao, Yiping
N1 - Publisher Copyright:
© 2020 IEEE
PY - 2020
Y1 - 2020
N2 - We have developed and evaluated a prototype animal PET dedicated for PET/CT/RT. It consists of 12 detectors configured in a dodecagon; each panel has a 30x30 array of 1x1x20 mm3 LYSO scintillators with each end of the scintillator array optically connected to Silicon Photomultiplier (SiPM) arrays for depth-of-interaction (DOI) measurement. The trans-axial and axial field-of-view (FOV) are ~10 cm in diameter and 3.5 cm long. PCB and FPGA based detector readout and processing electronics has been developed. Preliminary system and imaging performances were evaluated with a Na-22 point source and a F-18 ultra-micro hot-rod phantom. The energy, DOI, and coincidence timing resolutions of the system are around 23%, 3.2 mm, and 4.88 ns, respectively. The measured system sensitivity is ~2.2% at the center of FOV, and the image resolution measured from the reconstructed point source images over the FOV ranges from 0.77 to 1.03 mm (mean 0.83 mm). Hot-rods with diameters from 1.0 to 2.4 mm are well separated on the reconstructed phantom image when DOI is applied.
AB - We have developed and evaluated a prototype animal PET dedicated for PET/CT/RT. It consists of 12 detectors configured in a dodecagon; each panel has a 30x30 array of 1x1x20 mm3 LYSO scintillators with each end of the scintillator array optically connected to Silicon Photomultiplier (SiPM) arrays for depth-of-interaction (DOI) measurement. The trans-axial and axial field-of-view (FOV) are ~10 cm in diameter and 3.5 cm long. PCB and FPGA based detector readout and processing electronics has been developed. Preliminary system and imaging performances were evaluated with a Na-22 point source and a F-18 ultra-micro hot-rod phantom. The energy, DOI, and coincidence timing resolutions of the system are around 23%, 3.2 mm, and 4.88 ns, respectively. The measured system sensitivity is ~2.2% at the center of FOV, and the image resolution measured from the reconstructed point source images over the FOV ranges from 0.77 to 1.03 mm (mean 0.83 mm). Hot-rods with diameters from 1.0 to 2.4 mm are well separated on the reconstructed phantom image when DOI is applied.
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U2 - 10.1109/NSS/MIC42677.2020.9507964
DO - 10.1109/NSS/MIC42677.2020.9507964
M3 - Conference contribution
AN - SCOPUS:85124686034
T3 - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2020
BT - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2020
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2020
Y2 - 31 October 2020 through 7 November 2020
ER -