A fork in the road to fertility

R. L. Prueitt; A. R. Zinn

doi:10.1038/84735

A fork in the road to fertility

R. L. Prueitt, A. R. Zinn

Research output: Contribution to journal › Short survey › peer-review

50 Scopus citations

Abstract

Haploinsufficiency of FOXL2, a new forkhead transcription factor, causes blepharophimosis/ptosis/epicanthus inversus syndrome (BPES), a rare developmental disorder affecting the eyelid and sometimes the ovary. A new study implicates FOXL2 as the first human gene required for the maintenance of ovarian follicles. The discovery of FOXL2 may provide insight into the causes of idiopathic premature ovarian failure, a disease that burdens many infertile couples.

Original language	English (US)
Pages (from-to)	132-134
Number of pages	3
Journal	Nature genetics
Volume	27
Issue number	2
DOIs	https://doi.org/10.1038/84735
State	Published - Feb 27 2001

ASJC Scopus subject areas

Genetics

Access to Document

10.1038/84735

Cite this

@article{50bed106c7364a1f8c950aa3013b5cff,

title = "A fork in the road to fertility",

abstract = "Haploinsufficiency of FOXL2, a new forkhead transcription factor, causes blepharophimosis/ptosis/epicanthus inversus syndrome (BPES), a rare developmental disorder affecting the eyelid and sometimes the ovary. A new study implicates FOXL2 as the first human gene required for the maintenance of ovarian follicles. The discovery of FOXL2 may provide insight into the causes of idiopathic premature ovarian failure, a disease that burdens many infertile couples.",

author = "Prueitt, {R. L.} and Zinn, {A. R.}",

year = "2001",

month = feb,

day = "27",

doi = "10.1038/84735",

language = "English (US)",

volume = "27",

pages = "132--134",

journal = "Nature genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "2",

}

TY - JOUR

T1 - A fork in the road to fertility

AU - Prueitt, R. L.

AU - Zinn, A. R.

PY - 2001/2/27

Y1 - 2001/2/27

N2 - Haploinsufficiency of FOXL2, a new forkhead transcription factor, causes blepharophimosis/ptosis/epicanthus inversus syndrome (BPES), a rare developmental disorder affecting the eyelid and sometimes the ovary. A new study implicates FOXL2 as the first human gene required for the maintenance of ovarian follicles. The discovery of FOXL2 may provide insight into the causes of idiopathic premature ovarian failure, a disease that burdens many infertile couples.

AB - Haploinsufficiency of FOXL2, a new forkhead transcription factor, causes blepharophimosis/ptosis/epicanthus inversus syndrome (BPES), a rare developmental disorder affecting the eyelid and sometimes the ovary. A new study implicates FOXL2 as the first human gene required for the maintenance of ovarian follicles. The discovery of FOXL2 may provide insight into the causes of idiopathic premature ovarian failure, a disease that burdens many infertile couples.

UR - http://www.scopus.com/inward/record.url?scp=0035136679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035136679&partnerID=8YFLogxK

U2 - 10.1038/84735

DO - 10.1038/84735

M3 - Short survey

C2 - 11175772

AN - SCOPUS:0035136679

SN - 1061-4036

VL - 27

SP - 132

EP - 134

JO - Nature genetics

JF - Nature genetics

IS - 2

ER -

A fork in the road to fertility

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this