A direct radioimmunoassay of corticosterone in rat serum

C. Gomez Sanchez, B. A. Murry, D. C. Kem, Norman M Kaplan

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


A direct radioimmunoassay of cortico-sterone is described requiring as little as 1–2 μl of rat serum. After methanol inactivation of CBG, serum was assayed with a relatively specific antibody raised against corticosterone-21-hemisuccinate. While this antibody has a significant cross-reaction with cortisol, prior purification is not necessary since cortisol is not produced in the rat.

Original languageEnglish (US)
Pages (from-to)796-798
Number of pages3
Issue number3
StatePublished - Mar 1975

ASJC Scopus subject areas

  • Endocrinology


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