12(S),20-DiHETE, prepared by a combination of Evans-Crimmins asymmetric alkylation, Sonogashira alkynation, and Suzuki-Miyaura cross-coupling, significantly sensitizes phenylephrine-induced vasoconstriction of rat renal interlobar arteries.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Sep 13 2004|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry