TY - JOUR
T1 - A cluster of cases of Mycobacterium chelonei keratitis associated with outpatient office procedures
AU - Newman, Philip E.
AU - Goodman, Richard A.
AU - Waring, George O.
AU - Finton, Robert J.
AU - Wilson, Louis A.
AU - Wright, John
AU - Cavanagh, Harrison D
N1 - Funding Information:
Accepted for publication Jan. 3, 1984. From the Department of Ophthalmology, Emory University (Drs. Newman, Waring, Wilson, Wright, and Cavanagh); the Division of Field Services, Epidemiology Program Office, Centers for Disease Control, and Office of Epidemiology, Georgia Department of Human Resources (Dr. Goodman); and the Office of Epidemiology, FUlton County Health Department (Mr. Finton), Atlanta, Georgia. This study was supported in part by National Research Service Award EY05658-01 from the National Institutes of Health (Dr. Newman). Dr. Newman was a Heed Foundation Fellow (1983). Reprint requests to Philip E. Newman, M.D., Department of Ophthalmology, Emory University, 1339 Clifton Rd., N.E., Atlanta, GA 30322.
PY - 1984/3
Y1 - 1984/3
N2 - We studied three cases of keratitis caused by Mycobacterium chelonei, a nontuberculous mycobacterial species. The cases occurred in two women, 76 and 80 years old, and one man, 67 years old, treated as outpatients in the same office. One case followed suture removal and the other two occurred after posterior capsulotomy. Corneal lesions appeared within two to three weeks of trauma and were white, round infiltrates with indistinct margins and radiating projections. The lesions were found at all levels of the stroma and were associated with an epithelial defect. Anterior chamber reaction varied from a minimal response to a hypopyon. One patient responded to topical therapy with amikacin and erythromycin, but the other two patients required penetrating keratoplasties because of deep abscesses, which progressed toward the sclera despite therapy. These cases emphasized the possibility of rapidly growing nontuberculous mycobacteria producing serious ocular infections.
AB - We studied three cases of keratitis caused by Mycobacterium chelonei, a nontuberculous mycobacterial species. The cases occurred in two women, 76 and 80 years old, and one man, 67 years old, treated as outpatients in the same office. One case followed suture removal and the other two occurred after posterior capsulotomy. Corneal lesions appeared within two to three weeks of trauma and were white, round infiltrates with indistinct margins and radiating projections. The lesions were found at all levels of the stroma and were associated with an epithelial defect. Anterior chamber reaction varied from a minimal response to a hypopyon. One patient responded to topical therapy with amikacin and erythromycin, but the other two patients required penetrating keratoplasties because of deep abscesses, which progressed toward the sclera despite therapy. These cases emphasized the possibility of rapidly growing nontuberculous mycobacteria producing serious ocular infections.
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U2 - 10.1016/0002-9394(84)90634-2
DO - 10.1016/0002-9394(84)90634-2
M3 - Article
C2 - 6702973
AN - SCOPUS:0021356893
SN - 0002-9394
VL - 97
SP - 344
EP - 348
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 3
ER -