A carbamazepine trial in chronic, treatment-refractory schizophrenia

J. Sramek, J. Herrera, J. Costa, C. Heh, T. Tran-Johnson, G. Simpson

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Carbamazepine was given to 12 chronic, treatment-refractory schizophrenic patients for 5 weeks. No overall change was found, but four patients significantly improved while eight worsened. Given the paucity of successful treatments for refractory schizophrenia, further study of carbamazepine appears warranted.

Original languageEnglish (US)
Pages (from-to)748-750
Number of pages3
JournalAmerican Journal of Psychiatry
Issue number6
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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