GALACTOSYLTRANSFERASE has been studied in human serum, and early reports failed to demonstrate an elevation of total serum galactosyltransferase in malignant disease.12 Subsequent electrophoretic studies from this laboratory revealed that, although the majority of the serum enzyme runs as a single broad peak on polyacrylamide gels, serum specimens from patients with cancer contain a second and electrophoretically distinct isoenzyme, referred to as galactosyltransferase isoenzyme II (or GT-II).34 In this report these initial findings are extended, and we present results on 387 patients with malignant and nonmalignant disorders, confirming the correlation of GT-II with cancer. Materials and Methods Patient Material Serum.
|Original language||English (US)|
|Number of pages||3|
|Journal||New England Journal of Medicine|
|State||Published - Sep 28 1978|
ASJC Scopus subject areas