Biochemistry, Genetics and Molecular Biology
Adeno Associated Virus
50%
AMP-activated Protein Kinase
25%
Capsid
8%
Drug Megadose
29%
Expression Cassette
16%
Gene Expression
12%
Gene Targeting
8%
Gene Therapy
100%
Genetic Disorder
25%
Knockout Mouse
39%
Lifespan
12%
Low Drug Dose
10%
MECP2
58%
MicroRNA
25%
Mouse
47%
Mouse Model
25%
Promoter Region
8%
Regulatory Element
31%
Rett Syndrome
56%
Serotype
25%
Transfer Gene
18%
Transgene
18%
Virus Genome
18%
Wild Type Mouse
18%
Keyphrases
AAV Capsid
6%
Adeno-associated Viral
7%
Adeno-associated Viral Vector
9%
Adenovirus
25%
Alcohol-preferring
25%
Central Nervous System
28%
Clinical Model
25%
Clinical Translation
6%
Clinical Trials
12%
Dose Effect
9%
Dose-dependent Toxicity
6%
Duplication
6%
Efficacy Assessment
6%
Female Adults
6%
Female Mice
6%
Five Decades
6%
Gene Delivery
6%
Gene Therapy
75%
Gene Transfer
25%
Genetic Disease
25%
Genome Mining
6%
Genomic DNA (gDNA)
6%
High Dose
6%
Immunosuppression
12%
Inactivating mutation
9%
Interdependent Risks
6%
Intrathecal Administration
6%
Knock-in Mouse Model
25%
MECP2 Gene
31%
Methyl-CpG-binding Protein 2 (MeCP2)
36%
Multiple Dose
6%
Multiple Treatments
6%
Postnatal Day
6%
Preclinical Application
6%
Promising Strategies
6%
Protein Analysis
6%
Protein Expression
6%
Recombinant Adeno-associated Virus (rAAV)
12%
Regulated Genes
6%
Regulatory Approval
6%
Rett Syndrome
50%
Safety Study
6%
Self-complementary
6%
Stride Time
6%
Swing Time
6%
Systems Genetics
25%
Transgene Overexpression
6%
Treatment Age
16%
Treatment Paradigms
7%
Viral Genome
9%
Neuroscience
Adeno Associated Virus Vector
8%
Adeno-Associated Virus
75%
Adverse Effect
6%
AMP-activated Protein Kinase
25%
Angelman Syndrome
6%
Brain Development
6%
Cisterna Magna
25%
Cognitive Function
10%
Encephalopathy
6%
Fragile X Syndrome
6%
Gene Expression
6%
Gene Transfer
50%
Genomic DNA
6%
Immunosuppression
12%
In Vivo
15%
Intellectual Disability
6%
Intrathecal
6%
MECP2
70%
Methyl CpG Binding Protein 2
36%
MicroRNA
6%
Mosaicism
6%
Myc
6%
Neural Development
6%
Pervasive Developmental Disorder
6%
Problem Behavior
6%
Promoter Region
8%
Protein Expression
6%
Real-Time Polymerase Chain Reaction
6%
Rett Syndrome
100%
Transgene
6%
Virus Gene
12%
Virus Genome
15%
