Helmut Kramer

2023

Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila

Shekhar, S., Moehlman, A. T., Park, B., Ewnetu, M., Tracy, C., Titos, I., Pawłowski, K., Tagliabracci, V. S. & Krämer, H., Dec 2023, In: Nature communications. 14, 1, 2932.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A phosphoswitch at acinus-serine⁴³⁷ controls autophagic responses to cadmium exposure and neurodegenerative stress

Nandi, N., Zaidi, Z., Tracy, C. & Krämer, H., Jan 2022, In: eLife. 11, e72169.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Fic-mediated AMPylation tempers the unfolded protein response during physiological stress

Casey, A. K., Gray, H. F., Chimalapati, S., Hernandez, G., Moehlman, A. T., Stewart, N., Fields, H. A., Gulen, B., Servage, K. A., Stefanius, K., Blevins, A., Evers, B. M., Krämer, H. & Orth, K., Aug 9 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 32, e2208317119.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

In situ Dephosphorylation Assay with Recombinant Nil Phosphatase

Nandi, N., Tracy, C. & Krämer, H., Sep 20 2022, In: Bio-protocol. 12, 18, e4513.

Research output: Contribution to journal › Article › peer-review

STING controls energy stress-induced autophagy and energy metabolism via STX17

Rong, Y., Zhang, S., Nandi, N., Wu, Z., Li, L., Liu, Y., Wei, Y., Zhao, Y., Yuan, W., Zhou, C., Xiao, G., Levine, B., Yan, N., Mou, S., Deng, L., Tang, Z., Liu, X., Kramer, H. & Zhong, Q., Jul 4 2022, In: Journal of Cell Biology. 221, 7, e202202060.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2020

Hypersensitivity of Vps33B mutant flies to non-pathogenic infections is dictated by aberrant activation of p38b MAP kinase

Zhang, J., Tracy, C., Pasare, C., Zeng, J. & Krämer, H., Sep 1 2020, In: Traffic. 21, 9, p. 578-589 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation

Tyra, L. K., Nandi, N., Tracy, C. & Krämer, H., Mar 9 2020, In: Developmental cell. 52, 5, p. 605-616.e7

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2019

Drosophila p53 directs nonapoptotic programs in postmitotic tissue

Kurtz, P., Jones, A. E., Tiwari, B., Link, N., Wylie, A., Tracy, C., Krämer, H. & Abrams, J. M., 2019, In: Molecular biology of the cell. 30, 11, p. 1339-1351 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

The glial sodium-potassium-2-chloride cotransporter is required for synaptic transmission in the Drosophila visual system

Stenesen, D., Moehlman, A. T., Schellinger, J. N., Rodan, A. R. & Krämer, H., Dec 1 2019, In: Scientific reports. 9, 1, 2475.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2018

Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration

Moehlman, A. T., Casey, A. K., Servage, K., Orth, K. & Krämer, H., Jul 17 2018, In: eLife. 7, e38752.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Intracellular chloride and scaffold protein mo25 cooperatively regulate transepithelial ion transport through WNK signaling in the malpighian tubule

Sun, Q., Wu, Y., Jonusaite, S., Pleinis, J. M., Humphreys, J. M., He, H., Schellinger, J. N., Akella, R., Stenesen, D., Krämer, H., Goldsmith, E. J. & Rodan, A. R., May 2018, In: Journal of the American Society of Nephrology. 29, 5, p. 1449-1461 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

2017

Stress-induced Cdk5 activity enhances cytoprotective basal autophagy in Drosophila melanogaster by phosphorylating acinus at serine⁴³⁷

Nandi, N., Tyra, L. K., Stenesen, D. & Krämer, H., Dec 11 2017, In: eLife. 6, e30760.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2016

ARC Syndrome-Linked Vps33B Protein Is Required for Inflammatory Endosomal Maturation and Signal Termination

Akbar, M. A., Mandraju, R., Tracy, C., Hu, W., Pasare, C. & Krämer, H., 2016, In: Immunity. 45, 2, p. 267-279 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2015

The carcinine transporter CarT is required in Drosophila photoreceptor neurons to sustain histamine recycling

Stenesen, D., Moehlman, A. T. & Krämer, H., Dec 14 2015, In: eLife. 4, DECEMBER2015, e10972.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2014

Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy

Nandi, N., Tyra, L. K., Stenesen, D. & Krämer, H., 2014, In: Journal of Cell Biology. 207, 2, p. 253-268 16 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Drosophila melanogaster cellular repressor of E1A-stimulated genes is a lysosomal protein essential for fly development

Kowalewski-Nimmerfall, E., Schähs, P., Maresch, D., Rendic, D., Krämer, H. & Mach, L., Aug 27 2014, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 12, p. 2900-2912 13 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila

Takáts, S., Pircs, K., Nagy, P., Varga, Á., Kárpáti, M., Hegedus, K., Kramer, H., Kovács, A. L., Sass, M. & Juhász, G., Apr 15 2014, In: Molecular biology of the cell. 25, 8, p. 1338-1354 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

198 Scopus citations

Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis

Ham, H., Woolery, A. R., Tracy, C., Stenesen, D., Krämer, H. & Orth, K., 2014, In: Journal of Biological Chemistry. 289, 52, p. 36059-36069 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

2013

Microtubule-dependent endosomal sorting of clathrin-independent cargo by Hook1

Maldonado-Báez, L., Cole, N. B., Krämer, H. & Donaldson, J. G., Apr 15 2013, In: Journal of Cell Biology. 201, 2, p. 233-247 15 p.

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Route to destruction: Autophagosomes SNARE lysosomes

Krämer, H., May 2013, In: Journal of Cell Biology. 201, 4, p. 495-497 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2012

Drosophila mauve mutants reveal a role of LYST homologs late in the maturation of phagosomes and autophagosomes

Rahman, M., Haberman, A., Tracy, C., Ray, S. & Krämer, H., Dec 2012, In: Traffic. 13, 12, p. 1680-1692 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Kramer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journal › Article › peer-review

2885 Scopus citations

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Urban, D., Li, N., Christensen, H., Pluthero, F. G., Chen, S. Z., Puhacz, M., Garg, P. M., Lanka, K. K., Cummings, J. J., Kramer, H., Wasmuth, J. D., Parkinson, J. & Kahr, W. H. A., Dec 13 2012, In: Blood. 120, 25, p. 5032-5040 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

Burgess, J., Del Bel, L. M., Ma, C. I. J., Barylko, B., Polevoy, G., Rollins, J., Albanesi, J. P., Krämer, H. & Brill, J. A., Aug 15 2012, In: Development (Cambridge). 139, 16, p. 3040-3050 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

Burgess, J., Del Bel, L. M., Ma, C. I. J., Barylko, B., Polevoy, G., Rollins, J., Albanesi, J. P., Krämer, H. & Brill, J. A., Aug 15 2012, In: Journal of Cell Science. 125, 16, p. 3040-3050 11 p.

Research output: Contribution to journal › Article › peer-review

Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections

Rahman, M., Ham, H., Liu, X., Sugiura, Y., Orth, K. & Krämer, H., Jun 2012, In: Nature neuroscience. 15, 6, p. 871-875 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

2011

AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila

Burgess, J., Jauregui, M., Tan, J., Rollins, J., Lallet, S., Leventis, P. A., Boulianne, G. L., Chang, H. C., Borgne, R. L., Krämer, H. & Brill, J. A., Jun 15 2011, In: Molecular biology of the cell. 22, 12, p. 2094-2105 12 p.

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Hook2 is involved in the morphogenesis of the primary cilium

Baron Gaillard, C. L., Pallesi-Pocachard, E., Massey-Harroche, D., Richard, F., Arsanto, J. P., Chauvin, J. P., Lecine, P., Krämer, H., Borg, J. P. & Le Bivic, A., Dec 1 2011, In: Molecular biology of the cell. 22, 23, p. 4549-4562 14 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila

Akbar, M. A., Tracy, C., Kahr, W. H. A. & Krämer, H., Feb 7 2011, In: Journal of Cell Biology. 192, 3, p. 383-390 8 p.

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

2010

Drosophila acinus encodes a novel regulator of endocytic and autophagic trafficking

Haberman, A. S., Akbar, M. A., Ray, S. & Krämer, H., Jul 1 2010, In: Development. 137, 13, p. 2157-2166 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2009

The SM protein car/Vps33A regulates SNARE-mediated trafficking to lysosomes and lysosome-related organelles

Akbar, M. A., Ray, S. & Krämer, H., Mar 15 2009, In: Molecular biology of the cell. 20, 6, p. 1705-1714 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

2007

Hook2 contributes to aggresome formation

Szebenyi, G., Wigley, W. C., Hall, B., Didier, A., Yu, M., Thomas, P. & Krämer, H., May 31 2007, In: BMC Cell Biology. 8, 19.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function

Szebenyi, G., Hall, B., Yu, R., Hashim, A. I. & Krämer, H., Jan 2007, In: Traffic. 8, 1, p. 32-46 15 p.

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

The microtubule-binding protein hook3 interacts with a cytoplasmic domain of scavenger receptor A

Sano, H., Ishino, M., Krämer, H., Shimizu, T., Mitsuzawa, H., Nishitani, C. & Kuroki, Y., Mar 16 2007, In: Journal of Biological Chemistry. 282, 11, p. 7973-7981 9 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2005

A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila

Sevrioukov, E. A., Moghrabi, N., Kuhn, M. & Krämer, H., May 2005, In: Molecular biology of the cell. 16, 5, p. 2301-2312 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules

Pulipparacharuvil, S., Akbar, M. A., Ray, S., Sevrioukov, E. A., Haberman, A. S., Rohrer, J. & Krämer, H., Aug 15 2005, In: Journal of cell science. 118, 16, p. 3663-3673 11 p.

Research output: Contribution to journal › Article › peer-review

197 Scopus citations

2003

The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular trafficking

Shotland, Y., Krämer, H. & Groisman, E. A., Sep 2003, In: Molecular Microbiology. 49, 6, p. 1565-1576 12 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

2001

Molecular Characterization of Mammalian Homologues of Class C Vps Proteins That Interact with Syntaxin-7

Kim, B. Y., Krämer, H., Yamamoto, A., Kominami, E., Kohsaka, S. & Akazawa, C., Aug 3 2001, In: Journal of Biological Chemistry. 276, 31, p. 29393-29402 10 p.

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33

Huizing, M., Didier, A., Walenta, J., Anikster, Y., Gahl, W. A. & Krämer, H., Feb 21 2001, In: Gene. 264, 2, p. 241-247 7 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

The Golgi-associated Hook3 protein is a member of a novel family of microtubule-binding proteins

Walenta, J. H., Didier, A. J., Liu, X. & Krämer, H., Mar 5 2001, In: Journal of Cell Biology. 152, 5, p. 923-934 12 p.

Research output: Contribution to journal › Article › peer-review

161 Scopus citations

2000

Drosophila endosomal proteins hook and deep orange regulate synapse size but not synaptic vesicle recycling

Narayanan, R., Krämer, H. & Ramaswami, M., Nov 5 2000, In: Journal of Neurobiology. 45, 2, p. 105-119 15 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

1999

A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila

Sevrioukov, E. A., He, J. P., Moghrabi, N., Sunio, A. & Krämer, H., Oct 1999, In: Molecular cell. 4, 4, p. 479-486 8 p.

Research output: Contribution to journal › Article › peer-review

181 Scopus citations

Genetic analysis of hook, a gene required for endocytic trafficking in Drosophila

Krämer, H. & Phistry, M., Feb 1999, In: Genetics. 151, 2, p. 675-684 10 p.

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Genetic dissection of endocytic trafficking in drosophila using a horseradish peroxidase-Bride of Sevenless chimera: hook is required for normal maturation of multivesicular endosomes

Sunio, A., Metcalf, A. B. & Krämer, H., Apr 1999, In: Molecular biology of the cell. 10, 4, p. 847-859 13 p.

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

1998

Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery

Lloyd, V., Ramaswami, M. & Krämer, H., Dec 1 1998, In: Trends in Cell Biology. 8, 7, p. 257-259 3 p.

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

Oligomerization of the extracellular domain of Boss enhances its binding to the Sevenless receptor and its antagonistic effect on R7 induction

Sevrioukov, E. A., Walenta, J. H., Sunio, A., Phistry, M. & Krämer, H., 1998, In: Journal of cell science. 111, 6, p. 737-747 11 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

1996

Mutations in the Drosophila hook gene inhibit endocytosis of the boss transmembrane ligand into multivesicular bodies

Krämer, H. & Phistry, M., 1996, In: Journal of Cell Biology. 133, 6, p. 1205-1215 11 p.

Research output: Contribution to journal › Article › peer-review

127 Scopus citations

1994

Determination of photoreceptor cell fate in the Drosophila retina

Krämer, H. & Cagan, R. L., 1994, In: Current Opinion in Neurobiology. 4, 1, p. 14-20 7 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

1993

Extracellular domain of the boss transmembrane ligand acts as an antagonist of the sev receptor

Hart, A. C., Krämer, H. & Zipursky, S. L., 1993, In: Nature. 361, 6414, p. 732-736 5 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Patrilocal^* * patrilocal: taking the bride to the husband's home village cell-cell interactions: sevenless captures its bride

Kramer, H., Apr 1993, In: Trends in Cell Biology. 3, 4, p. 103-105 3 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Helmut Kramer

Research output

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