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Center for the Genetics of Host Defense
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Dive into the research topics where Bruce A Beutler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency
Lin, E. B., Meregini, S., Zhang, Z., Roy, A., Argula, T., Mitchell, J. M., Israelsen, W. J., Ludwig, S., Russell, J., Quan, J., Hildebrand, S., Nair-Gill, E., Beutler, B. & SoRelle, J. A., Jul 2025, In: JCI Insight. 10, 14, e180752.Research output: Contribution to journal › Article › peer-review
Open Access -
GPR45 modulates Gαs at primary cilia of the paraventricular hypothalamus to control food intake
Xun, Y., Jiang, Y., Xu, B., Tang, M., Ludwig, S., Nakamura, K., Mukhopadhyay, S., Liu, C., Beutler, B. & Zhang, Z., Jun 5 2025, In: Science. 388, 6751, eadp3989.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations -
Nonredundant Role of Leishmanolysin-Like (Lmln) Zinc-Metallopeptidase in Retinal Homeostasis
Ufret-Vincenty, R. L., Kirman, D. C., Ulker-Yilmazer, G., Aredo, B., Shrestha, S., Turpin, E., Yuksel, S., Zegeye, Y., Ludwig, S., Moresco, E. M. Y., He, Y. G. & Beutler, B., Jan 2025, In: American journal of ophthalmology. 269, p. 147-160 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural insights into GM4951 as a lipid droplet GTPase regulating hepatic lipid metabolism
Raj, R., Jiang, Y., Jha, R. K., Moresco, E. M. Y., Joshi, H., Zhang, Z. & Beutler, B., Dec 2025, In: Nature communications. 16, 1, 11458.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural insights into the ubiquitin-independent midnolin-proteasome pathway
Peddada, N., Zhong, X., Yin, Y., Lazaro, D. R., Wang, J., Lyon, S., Choi, J. H., Bai, X. C., Moresco, E. M. Y. & Beutler, B., May 13 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 19, e2505345122.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations